Full Prescribing Information

Prescribing Information   

Composition:

Tafecta: Each tablet contains TenofovirAlafenamide 25 mg

Clinical Pharmacology:

Tenofoviralafenamidefumarate (TAF) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir. Following oral administration, TAF is converted in vivo to tenofovir, an acyclic nucleoside phosphonate (nucleotide) analog of adenosine 5′-monophosphate. Tenofovir mimics normal DNA building blocks but is lacking a 3′-OH molecule required for phosphodiester bond linkage. By competing with regular nucleotides for incorporation into proviral DNA and prevention of the formation of the 5′ to 3′ phosphodiester linkage required for DNA elongation, tenofovir causes early chain termination and prevents proviral DNA transcription.

CORPORATE ADDRESS

Beacon Pharmaceuticals Limited
9/A,Toyenbee Circular Road,
Motijheel,Dhaka-1208, Bangladesh.
Phone: +880-2-57165371-79
Fax: +880 2-57165380
Web: beaconpharma.com.bd

ALTERNATIVE CONTACT 1

Skype ID: shahariar_tamal
WhatsApp: +8801922121404
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Email: [email protected]
[email protected]

ALTERNATIVE CONTACT 2

Skype ID: masfikur.rahman
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Email: [email protected]